Re: [pyrnet] help blood samples need for DNA

["mklimek" <mklimek@telusplanet.net>]

Hi Joe
Multifocal retropathy is an eye problem. Great Pyrenees are the only breed
to have this. It is inherit. It is autosomal recessive. It can be picked up
at 12 to 13 weeks of age with an eye examination. So far to date none have
developed it after this time.  A puppy can be normal at 8 weeks and then
have it at 12 weeks.It takes an eye exam to find it. The amount of vision
impairment varies to the degree that the dog has the disease.To date I have
not seen a blind dog with it but that does not mean there are none. They
seem to walk or run with there heads closer to the ground at in twilight
conditions. I have housed the research animals for Dr Grahn and can say that
the ones we have had here can function in a pet environment. One of the
original dogs was a working sheep dog when we found her. I have seen it in
various pedigrees. We have seen it in show dogs, working dogs and companion
dogs.
----- Original Message -----
From: <JGentzel@aol.com>
To: <pyrnet-l@pyrnet.org>
Sent: Saturday, November 25, 2000 5:12 AM
Subject: Re: [pyrnet] help blood samples need for DNA


> In a message dated 11/24/00 10:11:26 AM Eastern Standard Time,
> mklimek@telusplanet.net writes:
>
> << Dr Grahn is in need of blood samples from dogs who have been certified
to
> have multifocal retropathy These sample would be used for a DNA study to
> isolate the gene. >>
>
> Hi Marie
>
> Why don't you tell us something about multifocal retropathy.  Has it been
> identified in Pyrs?  Its name suggests to me it is eye related.  The breed
> basically has not tested eyes very much.  Until just over a year ago the
> "official word" was that cataracts and PRA did not occur in the breed.
Now
> it is established as occuring across North America and testing must be
done
> to identify and educate owners and breeders.
>
> Joe
>
>
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