Jan,. this is a Bernese Mountain Dog site, but it has MANY good links to vet info including Auto-Immune problems. I think you will find it helpful C. Colette Wilson Avignon Reg'd Kennels Great Pyrenees & Berger des Pyrenees Kitchener, Ontario, Canada mailto:avignon@bond.net http://www.bond.net/~warrickw/avignon/avignon.html